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Modulation of Brain Hyperexcitability: Potential New Therapeutic Approaches in Alzheimer’s Disease

People with Alzheimer’s disease (AD) have significantly higher rates of subclinical and overt epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal hyperexcitability even in the early phases of the disease. Such aberrant activity subsequently leads to downstream a...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Toniolo, Sofia, Sen, Arjune, Husain, Masud
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730926/
https://ncbi.nlm.nih.gov/pubmed/33297460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239318
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