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Effectiveness in Block by Dexmedetomidine of Hyperpolarization-Activated Cation Current, Independent of Its Agonistic Effect on α(2)-Adrenergic Receptors
Dexmedetomidine (DEX), a highly selective agonist of α(2)-adrenergic receptors, has been tailored for sedation without risk of respiratory depression. Our hypothesis is that DEX produces any direct perturbations on ionic currents (e.g., hyperpolarization-activated cation current, I(h)). In this stud...
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| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730867/ https://ncbi.nlm.nih.gov/pubmed/33266068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239110 |
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