Global hypermethylation of intestinal epithelial cells is a hallmark feature of neonatal surgical necrotizing enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) remains one of the overall leading causes of death in premature infants, and the pathogenesis is unpredictable and not well characterized. The aim of our study was to determine the molecular phenotype of NEC via transcriptomic and epithelial cell-specific...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Good, Misty, Chu, Tianjiao, Shaw, Patricia, McClain, Lora, Chamberlain, Austin, Castro, Carlos, Rimer, Jamie M., Mihi, Belgacem, Gong, Qingqing, Nolan, Lila S., Cooksey, Krista, Linneman, Laura, Agrawal, Pranjal, Finegold, David N., Peters, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730811/
https://ncbi.nlm.nih.gov/pubmed/33308304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00983-6
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