Global hypermethylation of intestinal epithelial cells is a hallmark feature of neonatal surgical necrotizing enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) remains one of the overall leading causes of death in premature infants, and the pathogenesis is unpredictable and not well characterized. The aim of our study was to determine the molecular phenotype of NEC via transcriptomic and epithelial cell-specific...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Good, Misty, Chu, Tianjiao, Shaw, Patricia, McClain, Lora, Chamberlain, Austin, Castro, Carlos, Rimer, Jamie M., Mihi, Belgacem, Gong, Qingqing, Nolan, Lila S., Cooksey, Krista, Linneman, Laura, Agrawal, Pranjal, Finegold, David N., Peters, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730811/
https://ncbi.nlm.nih.gov/pubmed/33308304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00983-6
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