Global hypermethylation of intestinal epithelial cells is a hallmark feature of neonatal surgical necrotizing enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) remains one of the overall leading causes of death in premature infants, and the pathogenesis is unpredictable and not well characterized. The aim of our study was to determine the molecular phenotype of NEC via transcriptomic and epithelial cell-specific...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Good, Misty, Chu, Tianjiao, Shaw, Patricia, McClain, Lora, Chamberlain, Austin, Castro, Carlos, Rimer, Jamie M., Mihi, Belgacem, Gong, Qingqing, Nolan, Lila S., Cooksey, Krista, Linneman, Laura, Agrawal, Pranjal, Finegold, David N., Peters, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730811/
https://ncbi.nlm.nih.gov/pubmed/33308304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00983-6
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