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Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
The RNA-dependent RNA polymerase (RdRp) is an essential enzyme for the viral replication process, catalyzing the viral RNA synthesis using a metal ion-dependent mechanism. In recent years, RdRp has emerged as an optimal target for the development of antiviral drugs, as demonstrated by recent approva...
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| Vydáno v: | Molecules |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730706/ https://ncbi.nlm.nih.gov/pubmed/33287144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235695 |
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