Liposomes Composed by Membrane Lipid Extracts from Macrophage Cell Line as a Delivery of the Trypanocidal N,N’-Squaramide 17 towards Trypanosoma cruzi

Chagas is a neglected tropical disease caused by Trypanosoma cruzi, and affects about 25 million people worldwide. N, N’-Squaramide 17 (S) is a trypanocidal compound with relevant in vivo effectiveness. Here, we produced, characterized, and evaluated cytotoxic and trypanocidal effects of macrophage-...

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Vydáno v:Materials (Basel)
Hlavní autoři: Quijia, Christian Rafael, Bonatto, Cínthia Caetano, Silva, Luciano Paulino, Andrade, Milene Aparecida, Azevedo, Clenia Santos, Lasse Silva, Camila, Vega, Manel, de Santana, Jaime Martins, Bastos, Izabela Marques Dourado, Carneiro, Marcella Lemos Brettas
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730638/
https://ncbi.nlm.nih.gov/pubmed/33276688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma13235505
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