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Acetaminophen-Induced Rat Hepatotoxicity Based on M1/M2-Macrophage Polarization, in Possible Relation to Damage-Associated Molecular Patterns and Autophagy

Overdose of acetaminophen (APAP), an antipyretic drug, is an important cause of liver injury. However, the mechanism in the rat model remains undetermined. We analyzed APAP-induced hepatotoxicity using rats based on M1/M2-macrophage functions in relation to damage-associated molecular patterns (DAMP...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Tsuji, Yuka, Kuramochi, Mizuki, Golbar, Hossain M., Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730394/
https://ncbi.nlm.nih.gov/pubmed/33256230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238998
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