NPM1-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?

Nucleophosmin (NPM1) gene mutations rarely occur in non-acute myeloid neoplasms (MNs) with <20% blasts. Among nearly 10,000 patients investigated so far, molecular analyses documented NPM1 mutations in around 2% of myelodysplastic syndrome (MDS) cases, mainly belonging to MDS with excess of blast...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Forghieri, Fabio, Nasillo, Vincenzo, Paolini, Ambra, Bettelli, Francesca, Pioli, Valeria, Giusti, Davide, Gilioli, Andrea, Colasante, Corrado, Acquaviva, Gloria, Riva, Giovanni, Barozzi, Patrizia, Maffei, Rossana, Potenza, Leonardo, Marasca, Roberto, Fozza, Claudio, Tagliafico, Enrico, Trenti, Tommaso, Comoli, Patrizia, Longo, Giuseppe, Luppi, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730332/
https://ncbi.nlm.nih.gov/pubmed/33255988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238975
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