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The GABA(A)-Benzodiazepine Receptor Antagonist Flumazenil Abolishes the Anxiolytic Effects of the Active Constituents of Crocus sativus L. Crocins in Rats

Anxiety is a chronic severe psychiatric disorder. Crocins are among the various bioactive components of the plant Crocus sativus L. (Iridaceae) and their implication in anxiety is well-documented. However, which is the mechanism of action underlying the anti-anxiety effects of crocins remains unknow...

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Publicat a:Molecules
Autors principals: Pitsikas, Nikolaos, Tarantilis, Petros A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730330/
https://ncbi.nlm.nih.gov/pubmed/33266149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235647
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