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Enhancement in Phospholipase D Activity as a New Proposed Molecular Mechanism of Haloperidol-Induced Neurotoxicity

Membrane phospholipase D (PLD) is associated with numerous neuronal functions, such as axonal growth, synaptogenesis, formation of secretory vesicles, neurodegeneration, and apoptosis. PLD acts mainly on phosphatidylcholine, from which phosphatidic acid (PA) and choline are formed. In turn, PA is a...

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Foilsithe in:Int J Mol Sci
Main Authors: Krzystanek, Marek, Krzystanek, Ewa, Skałacka, Katarzyna, Pałasz, Artur
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730321/
https://ncbi.nlm.nih.gov/pubmed/33291692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239265
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