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Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis

In our previous study, temporin-GHaR (GHaR) showed potent antimicrobial activity with strong hemolytic toxicity. To overcome its weakness, we designed GHaR6R, GHaR7R, GHaR8R, GHaR9R, and GHaR9W by changing the number of positive charges and the hydrophobic surface of GHaR. With the exception of GHaR...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wei, Hanqi, Xie, Zhipeng, Tan, Xiuchuan, Guo, Ran, Song, Yanting, Xie, Xi, Wang, Rong, Li, Lushuang, Wang, Manchuriga, Zhang, Yingxia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730238/
https://ncbi.nlm.nih.gov/pubmed/33291521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235724
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