Sleep/Wake Behavior and EEG Signatures of the TgF344-AD Rat Model at the Prodromal Stage

Transgenic modification of the two most common genes (APPsw, PS1ΔE9) related to familial Alzheimer’s disease (AD) in rats has produced a rodent model that develops pathognomonic signs of AD without genetic tau-protein modification. We used 17-month-old AD rats (n = 8) and age-matched controls (AC, n...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kreuzer, Matthias, Keating, Glenda L., Fenzl, Thomas, Härtner, Lorenz, Sinon, Christopher G., Hajjar, Ihab, Ciavatta, Vincent, Rye, David B., García, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730237/
https://ncbi.nlm.nih.gov/pubmed/33291462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239290
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