Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency

Varicella-zoster virus (VZV) establishes lifelong neuronal latency in most humans world-wide, reactivating in one-third to cause herpes zoster and occasionally chronic pain. How VZV establishes, maintains and reactivates from latency is largely unknown. VZV transcription during latency is restricted...

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Vydáno v:Nat Commun
Hlavní autoři: Ouwendijk, Werner J. D., Depledge, Daniel P., Rajbhandari, Labchan, Lenac Rovis, Tihana, Jonjic, Stipan, Breuer, Judith, Venkatesan, Arun, Verjans, Georges M. G. M., Sadaoka, Tomohiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730162/
https://ncbi.nlm.nih.gov/pubmed/33303747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20031-4
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