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A One-Pot Three-Component Synthesis and Investigation of the In Vitro Mechanistic Anticancer Activity of Highly Functionalized Spirooxindole-Pyrrolidine Heterocyclic Hybrids

With an aim to develop more effective and affordable anticancer agents possessing a unique mechanism of action, we designed and synthesized derivatives of spirooxindole-pyrrolidine heterocyclic hybrids in good yields through a one-pot three-component (3+2) cycloaddition strategy. The synthesized com...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Kumar, Raju Suresh, M. Al-thamili, Dhaifallah, Almansour, Abdulrahman I., Arumugam, Natarajan, Mohammad, Faruq
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730040/
https://ncbi.nlm.nih.gov/pubmed/33261115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235581
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