Tolerance induction in memory CD4 T cells is partial and reversible

Memory T cells respond rapidly in part because they are less reliant on a heightened levels of costimulatory molecules. This enables rapid control of secondary infecting pathogens but presents challenges to efforts to control or silence memory CD4 T cells, for example in antigen‐specific tolerance s...

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Bibliographische Detailangaben
Veröffentlicht in:Immunology
Hauptverfasser: Gray, Joshua I., Al‐Khabouri, Shaima, Morton, Fraser, Clambey, Eric T., Gapin, Laurent, Matsuda, Jennifer L., Kappler, John W., Marrack, Philippa, Garside, Paul, Otto, Thomas D., MacLeod, Megan K.L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730012/
https://ncbi.nlm.nih.gov/pubmed/32931017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13263
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