Cell–cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness

Cell–cell fusion is a physiological process that is hijacked during oncogenesis and promotes tumour evolution. The main known impact of cell fusion is to promote the formation of metastatic hybrid cells following fusion between mobile leucocytes and proliferating tumour cells. We show here that cell...

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Pubblicato in:Sci Rep
Autori principali: Delespaul, Lucile, Gélabert, Caroline, Lesluyes, Tom, Le Guellec, Sophie, Pérot, Gaëlle, Leroy, Laura, Baud, Jessica, Merle, Candice, Lartigue, Lydia, Chibon, Frédéric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729932/
https://ncbi.nlm.nih.gov/pubmed/33303824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78502-z
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