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Cardioprotective Effect of Tangeretin by Inhibiting PTEN/AKT/mTOR Axis in Experimental Sepsis-Induced Myocardial Dysfunction

Sepsis aggregates undesirable immune response causing depression of ventricular myocardium and diastolic dysfunction. This present study examined the effect of a plant-derived flavone tangeretin (TG) on autophagy and reduction in myocardial dysfunction. The sepsis was induced by cecum ligation and p...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Shiroorkar, Predeepkumar Narayanappa, Afzal, Obaid, Kazmi, Imran, Al-Abbasi, Fahad A., Altamimi, Abdulmalik Saleh Alfawaz, Gubbiyappa, Kumar Shiva, Sreeharsha, Nagaraja
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729459/
https://ncbi.nlm.nih.gov/pubmed/33260422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235622
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