Pressure overload promotes cystatin C secretion of cardiomyocytes to regulate the MAPK signaling pathway and mediate cardiac hypertrophy

BACKGROUND: This study aimed to compare serum cystatin C (CysC) levels between hypertensive and non-hypertensive patients, and to explore the correlation between serum CysC and left ventricular hypertrophy (LVH). We also investigated the effects of pressure overload on cardiac expression and secreti...

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Опубликовано в: :Ann Transl Med
Главные авторы: Shen, Yi, Zhang, Xiaoyi, Li, Chenguang, Wang, Xiang, Ye, Yong, Yuan, Jie, Gong, Hui, Zou, Yunzeng, Ge, Junbo
Формат: Artigo
Язык:Inglês
Опубликовано: AME Publishing Company 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729345/
https://ncbi.nlm.nih.gov/pubmed/33313259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-7041
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