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Immune Reconstitution After Gene Therapy Approaches in Patients With X-Linked Severe Combined Immunodeficiency Disease

X-linked severe immunodeficiency disease (SCID-X1) is an inherited, rare, and life-threating disease. The genetic origin is a defect in the interleukin 2 receptor γ chain (IL2RG) gene and patients are classically characterized by absence of T and NK cells, as well as presence of partially-functional...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Blanco, Elena, Izotova, Natalia, Booth, Claire, Thrasher, Adrian James
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729079/
https://ncbi.nlm.nih.gov/pubmed/33329605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.608653
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