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Precise determination of input-output mapping for multimodal gene circuits using data from transient transfection

The mapping of molecular inputs to their molecular outputs (input/output, I/O mapping) is an important characteristic of gene circuits, both natural and synthetic. Experimental determination of such mappings for synthetic circuits is best performed using stably integrated genetic constructs. In mamm...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Stelzer, Christoph, Benenson, Yaakov
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728399/
https://ncbi.nlm.nih.gov/pubmed/33253149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008389
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