COX-2 Is Downregulated in Human Stenotic Aortic Valves and Its Inhibition Promotes Dystrophic Calcification

Calcific aortic valve disease (CAVD) is the result of maladaptive fibrocalcific processes leading to a progressive thickening and stiffening of aortic valve (AV) leaflets. CAVD is the most common cause of aortic stenosis (AS). At present, there is no effective pharmacotherapy in reducing CAVD progre...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Vieceli Dalla Sega, Francesco, Fortini, Francesca, Cimaglia, Paolo, Marracino, Luisa, Tonet, Elisabetta, Antonucci, Antonio, Moscarelli, Marco, Campo, Gianluca, Rizzo, Paola, Ferrari, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727817/
https://ncbi.nlm.nih.gov/pubmed/33255450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238917
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi