Study and Preparation of Multifunctional Poly(L-Lysine)@Hyaluronic Acid Nanopolyplexes for the Effective Delivery of Tumor Suppressive MiR-34a into Triple-Negative Breast Cancer Cells

Non-viral gene delivery using exogenous microRNAs is a potential strategy for fighting cancers with poor prognosis and which lack specific therapies, such as triple-negative breast cancer (TNBC). Herein we report the synthesis of six nontoxic electrostatic polymeric nanocapsules (P1 to P6) for micro...

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Detalhes bibliográficos
Publicado no:Materials (Basel)
Main Authors: Djafari, Jamila, Fernández-Lodeiro, Javier, Santos, Hugo M., Lorenzo, Julia, Rodriguez-Calado, Sergi, Bértolo, Emilia, Capelo-Martínez, José Luis, Lodeiro, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727712/
https://ncbi.nlm.nih.gov/pubmed/33255217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma13235309
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