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Updates on the diagnosis and management of the most common hereditary porphyrias: AIP and EPP

The porphyrias are a family of metabolic disorders caused by defects in the activity of one of the enzymes in the heme biosynthetic pathway. Acute intermittent porphyria (AIP), caused by autosomal dominant mutations in the gene encoding hydroxymethylbilane synthase, can lead to hepatocyte overaccumu...

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Detalhes bibliográficos
Publicado no:Hematology Am Soc Hematol Educ Program
Main Authors: Linenberger, Michael, Fertrin, Kleber Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727547/
https://ncbi.nlm.nih.gov/pubmed/33275677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/hematology.2020000124
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