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CTNNB1 Knockdown Inhibits Cell Proliferation and Aldosterone Secretion Through Inhibiting Wnt/β-Catenin Signaling in H295R Cells

Aldosterone-producing adenomas (APA) is one of the causative factors of primary aldosteronism. Previous studies have suggested that there are somatic CTNNB1 mutations in APA, but the specific mechanism of CTNNB1 mutation in APA tumorigenesis and aldosterone secretion remains unclear. In the present...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Technol Cancer Res Treat
Hauptverfasser: Zhou, Tingting, Luo, Pengwei, Wang, Liang, Yang, Shiwei, Qin, Shiyuan, Wei, Zhitao, Liu, Jiwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727057/
https://ncbi.nlm.nih.gov/pubmed/33287648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1533033820979685
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