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Lack of PTEN in osteocytes increases circulating phosphate concentrations by decreasing intact fibroblast growth factor 23 levels

Fibroblast growth factor 23 (FGF23) has been centric to the regulation of phosphate (Pi) metabolism; however, the regulatory network of FGF23 in osteocytes has not yet been defined in detail. We herein investigated the role of PTEN (phosphatase and tensin homolog deleted from chromosome 10) in this...

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Publicat a:Sci Rep
Autors principals: Kawai, Masanobu, Kinoshita, Saori, Ozono, Keiichi, Michigami, Toshimi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726559/
https://ncbi.nlm.nih.gov/pubmed/33299044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78692-6
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