Nrf2 Mediates Metabolic Reprogramming in Non-Small Cell Lung Cancer

Nuclear factor erythroid-2–related factor-2 (NFE2L2/Nrf2) is a transcription factor that regulates the expression of antioxidant genes. Both Kelch-like ECH-associated protein 1 (Keap1) mutations and Nrf2 mutations contribute to the activation of Nrf2 in non-small cell lung cancer (NSCLC). Nrf2 activ...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhao, Jiangang, Lin, Xu, Meng, Di, Zeng, Liping, Zhuang, Runzhou, Huang, Sha, Lv, Wang, Hu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726415/
https://ncbi.nlm.nih.gov/pubmed/33324555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.578315
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