The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies

Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer’s disease (AD) symptoms could improve disease detection and enable timely interventions. Changes in brain hemodynamics may be associated with the main clinical AD symptoms. To test this possibility, we measured the va...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tuovinen, Timo, Kananen, Janne, Rajna, Zalan, Lieslehto, Johannes, Korhonen, Vesa, Rytty, Riikka, Mattila, Heli, Huotari, Niko, Raitamaa, Lauri, Helakari, Heta, Elseoud, Ahmed Abou, Krüger, Johanna, LeVan, Pierre, Tervonen, Osmo, Hennig, Juergen, Remes, Anne M., Nedergaard, Maiken, Kiviniemi, Vesa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726142/
https://ncbi.nlm.nih.gov/pubmed/33298996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77984-1
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