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THERAPEUTIC POTENTIAL AND SAFETY CONSIDERATIONS FOR THE CLINICAL USE OF SYNTHETIC CANNABINOIDS

The phytocannabinoid Δ(9)-tetrahydrocannabinol (THC) was isolated and synthesized in the 1960s. Since then, two synthetic cannabinoids (SCBs) targeting the cannabinoid 1 (CB1R) and 2 (CB2R) receptors were approved for medical use based on clinical safety and efficacy data: dronabinol (synthetic THC)...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Sholler, Dennis J., Huestis, Marilyn A., Amendolara, Benjamin, Vandrey, Ryan, Cooper, Ziva D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725960/
https://ncbi.nlm.nih.gov/pubmed/33086126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2020.173059
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