Physical Modeling of a Sliding Clamp Mechanism for the Spreading of ParB at Short Genomic Distance from Bacterial Centromere Sites

Bacterial ParB partitioning proteins involved in chromosomes and low-copy-number plasmid segregation are cytosine triphosphate (CTP)-dependent molecular switches. CTP-binding converts ParB dimers to DNA clamps, allowing unidimensional diffusion along the DNA. This sliding property has been proposed...

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Bibliographic Details
Published in:iScience
Main Authors: Walter, Jean-Charles, Rech, Jérôme, Walliser, Nils-Ole, Dorignac, Jérôme, Geniet, Frédéric, Palmeri, John, Parmeggiani, Andrea, Bouet, Jean-Yves
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725951/
https://ncbi.nlm.nih.gov/pubmed/33319179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101861
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