Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy

The aim of the present study was to analyze copy number variations (CNV) of multiple oncogenes and tumor suppressor genes in genomic DNA from primary tumor tissue, lymph node metastasis and cell-free DNA (cfDNA) from serum of 72 urothelial carcinoma of bladder (UCB) patients treated with radical cys...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Soave, Armin, Kluwe, Lan, Yu, Hang, Rink, Michael, Gild, Philipp, Vetterlein, Malte W., Marks, Philipp, Sauter, Guido, Fisch, Margit, Meyer, Christian P., Ludwig, Tim, Dahlem, Roland, Minner, Sarah, Pantel, Klaus, Steinbach, Bettina, Schwarzenbach, Heidi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725833/
https://ncbi.nlm.nih.gov/pubmed/33298978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75869-x
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