Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo

In a secondary dengue virus (DENV) infection, the presence of non-neutralizing antibodies (Abs), developed during a previous infection with a different DENV serotype, is thought to worsen clinical outcomes by enhancing viral production. This phenomenon is called antibody-dependent enhancement (ADE)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kurosu, Takeshi, Hanabara, Keiko, Asai, Azusa, Pambudi, Sabar, Phanthanawiboon, Supranee, Omokoko, Magot Diata, Ono, Ken-ichiro, Saijo, Masayuki, Ramasoota, Pongrama, Ikuta, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725774/
https://ncbi.nlm.nih.gov/pubmed/33299049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78639-x
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