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H4K20me3 methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells

Heterochromatin, a densely packed chromatin state that is transcriptionally silent, is a critical regulator of gene expression. However, it is unclear how the repressive histone modification H4K20me3 or the histone methyltransferase SUV420H2 regulates embryonic stem (ES) cell fate by patterning the...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Kurup, Jiji T., Han, Zhijun, Jin, Wenfei, Kidder, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725612/
https://ncbi.nlm.nih.gov/pubmed/33144397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.188516
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