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In Situ Forming Implants exposed to Ultrasound Enhances Therapeutic Efficacy in Subcutaneous Murine Tumors

In situ forming implants (ISFIs) allow for a high initial intratumoral concentration and sustained release of the chemotherapeutic. However, clinical translation is impeded primarily due to limited drug penetration from the tumor/boundary interface and poor intratumoral drug retention. Therapeutic u...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Jeganathan, Selva, Budziszewski, Emily, Bielecki, Peter, Kolios, Michael C., Exner, Agata A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725358/
https://ncbi.nlm.nih.gov/pubmed/32389777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.05.003
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