A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN

Myeloid neoplasm (MPN) clones can evolve from acute myeloid leukemia to gain dominance with isocitrate dehydrogenase inhibition. Pro-differentiation agents such as ivosidenib can unmask MPN sequelae.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: Xiao, Wenbin, Miles, Linde A., Bowman, Robert L., Durani, Vidushi, Tian, Helen S., DelGaudio, Nicole L., Mishra, Tanmay, Zhu, Menglei, Zhang, Yanming, Stump, Sarah E., Tallman, Martin S., Levine, Ross L., Cai, Sheng F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2020
Pynciau:
Exceptional Case Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724900/
https://ncbi.nlm.nih.gov/pubmed/33284943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003326
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