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Allogeneic human umbilical cord Wharton’s jelly stem cells increase several-fold the expansion of human cord blood CD34+ cells both in vitro and in vivo

BACKGROUND: The transplantation of human umbilical cord blood (UCB) CD34+ cells has been successfully used to treat hematological disorders but one major limitation has been the low cell numbers available. Mesenchymal stem cells (MSCs) lying within the bone marrow in vivo behave like a scaffold on w...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Lin, Hao Daniel, Fong, Chui-Yee, Biswas, Arijit, Bongso, Ariff
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724853/
https://ncbi.nlm.nih.gov/pubmed/33298170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02048-0
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