A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis

Phagocytosis is a key function in various cells throughout the body. A deficiency in photoreceptor outer segment (POS) phagocytosis by the retinal pigment epithelium (RPE) causes vision loss in inherited retinal diseases and possibly age-related macular degeneration. To date, there are no effective...

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Udgivet i:Stem Cell Reports
Main Authors: Schreiter, Sven, Vafia, Katerina, Barsacchi, Rico, Tsang, Stephen H., Bickle, Marc, Ader, Marius, Karl, Mike O., Tanaka, Elly M., Almedawar, Seba
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724476/
https://ncbi.nlm.nih.gov/pubmed/33242397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.10.013
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