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ASIC3 inhibition modulates inflammation-induced changes in the activity and sensitivity of Aδ and C fiber sensory neurons that innervate bone

The Acid Sensing Ion Channel 3 (ASIC3) is a non-selective cation channel that is activated by acidification, and is known to have a role in regulating inflammatory pain. It has pro-algesic roles in a range of conditions that present with bone pain, but the mechanism for this has not yet been demonst...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Morgan, Michael, Thai, Jenny, Trinh, Phu, Habib, Mohamed, Effendi, Kelly N, Ivanusic, Jason J
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724402/
https://ncbi.nlm.nih.gov/pubmed/33280501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806920975950
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