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Calpains play an essential role in mechanical ventilation-induced diaphragmatic weakness and mitochondrial dysfunction

Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, an unintended consequence of prolonged MV is the rapid development of diaphragmatic atrophy and contractile dysfunction, known as ventilator-induced diaphragm dysfunction (VIDD). Although the m...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Hyatt, Hayden W., Ozdemir, Mustafa, Yoshihara, Toshinori, Nguyen, Branden L., Deminice, Rafael, Powers, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724197/
https://ncbi.nlm.nih.gov/pubmed/33279868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101802
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