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Tumor Necrosis Factor Receptors: Pleiotropic Signaling Complexes and Their Differential Effects

Since its discovery in 1975, TNFα has been a subject of intense study as it plays significant roles in both immunity and cancer. Such attention is well deserved as TNFα is unique in its engagement of pleiotropic signaling via its two receptors: TNFR1 and TNFR2. Extensive research has yielded mechani...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gough, Portia, Myles, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723893/
https://ncbi.nlm.nih.gov/pubmed/33324405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585880
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