Poncirin suppresses lipopolysaccharide (LPS)-induced microglial inflammation and ameliorates brain ischemic injury in experimental stroke in mice

BACKGROUND: Based on accumulating evidence, excessive activation of microglia-mediated inflammatory responses plays an essential role in ischemic stroke. Poncirin (Pon) exerts anti-hyperalgesic, anti-osteoporotic and anti-tumor effects on various diseases. However, the roles of Pon in microglial act...

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Bibliografiske detaljer
Udgivet i:Ann Transl Med
Main Authors: Yang, Li-Xuan, Chen, Fang-Yu, Yu, Hai-Long, Liu, Pin-Yi, Bao, Xin-Yu, Xia, Sheng-Nan, Gu, Yue, Xu, Yun, Cao, Xiang
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723616/
https://ncbi.nlm.nih.gov/pubmed/33313089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-3470
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