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Inhibition of Wnt signaling by Frizzled7 antibody-coated nanoshells sensitizes triple-negative breast cancer cells to the autophagy regulator chloroquine

Despite improvements in our understanding of the biology behind triple-negative breast cancer (TNBC), it remains a devastating disease due to lack of an effective targeted therapy. Inhibiting Wnt signaling is a promising strategy to combat TNBC because Wnt signaling drives TNBC progression, chemores...

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Detalhes bibliográficos
Publicado no:Nano Res
Main Authors: Wang, Jianxin, Dang, Megan N., Day, Emily S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723362/
https://ncbi.nlm.nih.gov/pubmed/33304449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12274-020-2795-8
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