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RNA structure-wide discovery of functional interactions with multiplexed RNA motif library

Biochemical assays and computational analyses have discovered RNA structures throughout various transcripts. However, the roles of these structures are mostly unknown. Here we develop folded RNA element profiling with structure library (FOREST), a multiplexed affinity assay system to identify functi...

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Vydáno v:Nat Commun
Hlavní autoři: Komatsu, Kaoru R., Taya, Toshiki, Matsumoto, Sora, Miyashita, Emi, Kashida, Shunnichi, Saito, Hirohide
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723054/
https://ncbi.nlm.nih.gov/pubmed/33293523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19699-5
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