Clinical, metabolic, and molecular genetic characterization of hereditary methemoglobinemia caused by cytochrome b(5) reductase deficiency in 30 dogs

Genotype–phenotype correlations of humans and dogs with hereditary methemoglobinemia are not yet well characterized. We determined total hemoglobin and methemoglobin (MetHb) concentrations, cytochrome b(5) reductase (CYB5R) enzyme activities, genotypes, and clinical signs in 30 dogs with persistent...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jaffey, J. A., Reading, N. S., Abdulmalik, O., Kreisler, R., Bullock, G., Wiest, A., Villani, N. A., Mhlanga-Mutangadura, T., Johnson, G. S., Cohn, L. A., Isaza, N., Harvey, J. W., Giger, U.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723051/
https://ncbi.nlm.nih.gov/pubmed/33293645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78391-2
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