Clinical, metabolic, and molecular genetic characterization of hereditary methemoglobinemia caused by cytochrome b(5) reductase deficiency in 30 dogs

Genotype–phenotype correlations of humans and dogs with hereditary methemoglobinemia are not yet well characterized. We determined total hemoglobin and methemoglobin (MetHb) concentrations, cytochrome b(5) reductase (CYB5R) enzyme activities, genotypes, and clinical signs in 30 dogs with persistent...

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書誌詳細
出版年:Sci Rep
主要な著者: Jaffey, J. A., Reading, N. S., Abdulmalik, O., Kreisler, R., Bullock, G., Wiest, A., Villani, N. A., Mhlanga-Mutangadura, T., Johnson, G. S., Cohn, L. A., Isaza, N., Harvey, J. W., Giger, U.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723051/
https://ncbi.nlm.nih.gov/pubmed/33293645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78391-2
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