An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas

Silencing of exogenous DNA can make transgene expression very inefficient. Genetic screens in the model alga Chlamydomonas have demonstrated that transgene silencing can be overcome by mutations in unknown gene(s), thus producing algal strains that stably express foreign genes to high levels. Here,...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Neupert, Juliane, Gallaher, Sean D., Lu, Yinghong, Strenkert, Daniela, Segal, Na’ama, Barahimipour, Rouhollah, Fitz-Gibbon, Sorel T., Schroda, Michael, Merchant, Sabeeha S., Bock, Ralph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722844/
https://ncbi.nlm.nih.gov/pubmed/33293544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19983-4
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