The antiplatelet agent revacept prevents the increase of systemic thromboxane A(2) biosynthesis and neointima hyperplasia

Neointima hyperplasia is a crucial component of restenosis after coronary angioplasty. We have hypothesized that enhanced generation of platelet-derived thromboxane (TX)A(2) in response to vascular damage plays a critical role in neointimal hyperplasia and that antiplatelet agents may mitigate it. I...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Alberti, Sara, Zhang, Qianqian, D’Agostino, Ilaria, Bruno, Annalisa, Tacconelli, Stefania, Contursi, Annalisa, Guarnieri, Simone, Dovizio, Melania, Falcone, Lorenza, Ballerini, Patrizia, Münch, Götz, Yu, Ying, Patrignani, Paola
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722842/
https://ncbi.nlm.nih.gov/pubmed/33293599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77934-x
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