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Reverse C-glycosidase reaction provides C-nucleotide building blocks of xenobiotic nucleic acids

C-Analogues of the canonical N-nucleosides have considerable importance in medicinal chemistry and are promising building blocks of xenobiotic nucleic acids (XNA) in synthetic biology. Although well established for synthesis of N-nucleosides, biocatalytic methods are lacking in C-nucleoside syntheti...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pfeiffer, Martin, Nidetzky, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722734/
https://ncbi.nlm.nih.gov/pubmed/33293530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20035-0
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