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In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons

The in vivo firing patterns of ventral midbrain dopamine neurons are controlled by afferent and intrinsic activity to generate sensory cue and prediction error signals that are essential for reward-based learning. Given the absence of in vivo intracellular recordings during the last three decades, t...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Otomo, Kanako, Perkins, Jessica, Kulkarni, Anand, Stojanovic, Strahinja, Roeper, Jochen, Paladini, Carlos A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722714/
https://ncbi.nlm.nih.gov/pubmed/33293613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20041-2
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