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Biglycan and chondroitin sulfate play pivotal roles in bone toughness via retaining bound water in bone mineral matrix

Recent in vitro evidence shows that glycosaminoglycans (GAGs) and proteoglycans (PGs) in bone matrix may functionally be involved in the tissue-level toughness of bone. In this study, we showed the effect of biglycan (Bgn), a small leucine-rich proteoglycan enriched in extracellular matrix of bone a...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Hua, Rui, Ni, Qingwen, Eliason, Travis D., Han, Yan, Gu, Sumin, Nicolella, Daniel P., Wang, Xiaodu, Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722036/
https://ncbi.nlm.nih.gov/pubmed/33002580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2020.09.002
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