Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival

Complex neural circuitry requires stable connections formed by lengthy axons. To maintain these functional circuits, fast transport delivers RNAs to distal axons where they undergo local translation. However, the mechanism that enables long-distance transport of RNA granules is not yet understood. H...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Fukuda, Yusuke, Pazyra-Murphy, Maria F., Silagi, Elizabeth S., Tasdemir-Yilmaz, Ozge E., Li, Yihang, Rose, Lillian, Yeoh, Zoe C., Vangos, Nicholas E., Geffken, Ezekiel A., Seo, Hyuk-Soo, Adelmant, Guillaume, Bird, Gregory H., Walensky, Loren D., Marto, Jarrod A., Dhe-Paganon, Sirano, Segal, Rosalind A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721913/
https://ncbi.nlm.nih.gov/pubmed/33284322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202005051
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