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Enrichment of plasma extracellular vesicles for reliable quantification of their size and concentration for biomarker discovery

Human plasma is a complex fluid, increasingly used for extracellular vesicle (EV) biomarker studies. Our aim was to find a simple EV-enrichment method for reliable quantification of EVs in plasma to be used as biomarker of disease. Plasma of ten healthy subjects was processed using sedimentation rat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Holcar, Marija, Ferdin, Jana, Sitar, Simona, Tušek-Žnidarič, Magda, Dolžan, Vita, Plemenitaš, Ana, Žagar, Ema, Lenassi, Metka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721811/
https://ncbi.nlm.nih.gov/pubmed/33288809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78422-y
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