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Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton
Previously, we showed that embryonic deletion of TGF-β type 2 receptor in mouse sclerotome resulted in defects in fibrous connective tissues in the spine. Here we investigated how TGF-β regulates expression of fibrous markers: Scleraxis, Fibromodulin and Adamtsl2. We showed that TGF-β stimulated exp...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7721728/ https://ncbi.nlm.nih.gov/pubmed/33288795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78206-4 |
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